
Methadone vs Suboxone. Why We Use Methadone
Buprenorphine and Suboxone are not legal to prescribe for addiction treatment in Thailand. Methadone is. This page explains what medication-assisted treatment means, which medications are available here, which are not, and how the clinical team uses them to get you through withdrawal.
- Psychiatrist-led assessment and an individualized medication plan within the first 24 hours
- Methadone taper available as the primary detox medication for opioid withdrawal
- Clinical Opiate Withdrawal Scale scoring through the taper to guide every dose change
- Cold turkey option for those who prefer it, with full comfort medication support


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What Is Medication-Assisted Treatment?
Medication-assisted treatment is the use of medication alongside therapy to manage opioid use disorder. The term covers a lot of ground. It stretches from a few days of detox support to years of maintenance, and the drugs used, the length of the course and the goal all change with the country and the treating team. Knowing what it means here, before you get on a plane, is what stops the first morning being a shock.
At Jintara the decision about which medication to use, if any, sits with the attending psychiatrist in the first hours after admission. The shape of it is a conversation between a doctor and a person, which Jintara's founder states directly, not a default prescription handed over at the desk.
The evidence for using medication during acute withdrawal is strong. NIDA's opioid research overview reports that opioid use disorder responds to medication, counselling and social support in combination, and that withdrawal managed with medication is safer and more tolerable than going without it for most people.

“A lot of clients come in thinking they can get off opioids in three days. They want a rapid detox. We know it takes at least three weeks.
How Do Methadone, Suboxone, and Naltrexone Differ?
Three medications carry most of the weight in opioid treatment internationally. They are methadone, buprenorphine and naltrexone, and they are not interchangeable.
Methadone is a long-acting opioid agonist. Inside a controlled taper it holds withdrawal in a range a person can actually sit with, while the shorter-acting opioid clears. Buprenorphine is usually combined with naloxone and sold as Suboxone. It is a partial agonist with a ceiling effect, so past a certain dose it stops adding effect, which is what makes it a steady medication to stay on for months. Naltrexone is an opioid antagonist. It blocks the effect of opioids and belongs after detox as a relapse prevention tool, never during it.
What any given medically supervised detox can actually put in your hand depends on local law and supply, not only on the evidence base.
NIDA's research report on medications for opioid use disorder sets out the case for using these medications alongside counselling, measured on retention in treatment, reduced illicit use and overdose prevention.
The global evidence base for these medications is settled. Which of them Jintara can supply is settled by Thai law.
The same three medications come up in every conversation about opioid treatment. They do different jobs, and only one of them is part of a detox at Jintara.
| Medication | What it does | Used at Jintara |
|---|---|---|
| Methadone | Full opioid agonist. Holds withdrawal steady, then steps down in stages. | Yes, as a short-term detox taper |
| Buprenorphine | Partial agonist with a ceiling effect. Built for long-term maintenance. | No, not legal to prescribe here |
| Naltrexone | Opioid antagonist. Blocks opioid effect after detox has finished. | No, not part of the model |
Methadone
What it does: Full opioid agonist. Holds withdrawal steady, then steps down in stages.
Used at Jintara: Yes, as a short-term detox taper
Buprenorphine
What it does: Partial agonist with a ceiling effect. Built for long-term maintenance.
Used at Jintara: No, not legal to prescribe here
Naltrexone
What it does: Opioid antagonist. Blocks opioid effect after detox has finished.
Used at Jintara: No, not part of the model
Is Suboxone Legal in Thailand?
Buprenorphine and Suboxone cannot legally be prescribed for addiction treatment in Thailand. That is a national regulatory position, not a gap in Jintara's formulary, and no private facility here works around it.
So if you arrive holding a Suboxone script from the UK, the United States or Australia, that script stops at the door. The clinical team tapers you off buprenorphine as part of admission rather than continuing a medication it is not legal to supply. The first methadone dose is timed so leftover buprenorphine does not collide with it, a precipitated-withdrawal risk that SAMHSA TIP 63 flags when opioid agonists are stacked. For anyone coming out of a system where buprenorphine maintenance is standard and unremarkable, this is the single most important thing to know before booking.
Methadone is legal here and Jintara uses it. Naltrexone is not part of the treatment model here, and naltrexone implants are not used. Nobody should meet that fact for the first time on arrival, which is why the first week of treatment opens with a plain conversation about what your detox is going to look like.

How Does Methadone Compare With Suboxone in a Detox?
Methadone vs Suboxone is not a brand pick at Jintara. Methadone is a full opioid agonist. Buprenorphine, the opioid in Suboxone, is a partial one. That single difference shapes the whole withdrawal curve, which is why the taper here uses methadone rather than trying to copy a Suboxone plan that Thai law will not let it fill.
A full agonist keeps acting as the dose goes up, so a taper can be set high enough to hold someone steady through the worst of it and then stepped down in stages. A partial agonist has a ceiling. Past a point it stops adding effect, which makes it a stable thing to sit on for months and a blunter instrument for bringing someone down over weeks. Methadone also has a long half life, which is why the taper is counted in weeks rather than days.
That difference is the reasoning behind the taper used here, inside the opioid treatment program. The psychiatrist builds the schedule from the opioid used, the dose and how long it has been used, and Clinical Opiate Withdrawal Scale scores taken several times a day in the early phase guide each adjustment.
Head Nurse Lertkhwan Sukpia oversees medication administration throughout detox. Every score and every dose change is logged by Lertkhwan Sukpia into the nursing record, which is the same record the opioid detox protocol and the opioid medication protocol run on.
Methadone carries a stigma in some markets, particularly with UK clients who know it as the maintenance queue. What happens here is a different thing: a clinical taper of defined length, under nursing supervision, with an end date. The same shape is described in the NHS guidance on methadone, a dose reduced gradually until it is no longer needed, and it can run quicker in a residential setting than in community treatment. People who arrive sceptical often change position within a few days of feeling withdrawal without it.
Why Maintenance Medication Is Not Part of Your Discharge Plan.
Jintara does not recommend naltrexone, acamprosate or oral relapse prevention medication as part of the discharge plan.
The clinical position, stated by Denise O'Leary, is direct: "We don't recommend using substances to treat substances." That is a clinical philosophy, not a claim that those drugs fail. They work, for the right person in the right context. The position here is that the 30-day program should build the psychological tools, the relapse prevention plan and the aftercare structure that hold up without an ongoing prescription behind them. Naloxone kits are not provided at discharge.
This is particular to Jintara and it is not a global consensus, which the team says out loud rather than burying. For some people, especially those with a long history of high-dose opioid use, extended-release naltrexone or buprenorphine maintenance at home may be exactly the right aftercare. Where that is clinically indicated the team raises it honestly and asks you to take it to your GP or addiction specialist at home.
What you get instead is a relapse prevention plan built during the final weeks of treatment, an aftercare referral network, and a clinical team that is straight about what works for whom.
What Does Cold Turkey Opioid Detox Involve?
Cold turkey opioid withdrawal, without a taper medication, is available at Jintara for people who want it. That does not mean going without medical support. The nursing team carries it with comfort medication, including clonidine for some of the physical symptoms and something for anxiety and sleep. It is opioid withdrawal without opioid-based taper medication, which is a different thing from being left alone with it.
The honest version is that it is considerably harder than a taper. Opioid withdrawal without agonist support follows its own delayed-peak pattern, and that pattern catches people out. The first 24 to 48 hours are often more manageable than anyone expects. Then days four to seven arrive with the full weight of it, the muscle aches, the insomnia, the sweating, the nausea and a physical restlessness that does not let you sit still. A lot of the people who start cold turkey ask to switch to methadone somewhere in those days, and the switch is available whenever they ask. There is no clinical barrier to changing your mind halfway through.
For someone with a shorter use history or a lower tolerance, cold turkey is sometimes the better call, and the psychiatrist works through both options at the admission assessment. Any underlying dual diagnosis is weighed at the same time, because anxiety or a mood disorder can make the cold turkey experience considerably harder than the substance history on its own would suggest.


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Common Questions About Medication and Opioid Detox
Jintara uses medically supervised medication during the opioid detox phase, primarily a methadone taper for people who choose it. Post-detox maintenance medications such as naltrexone or buprenorphine are not part of the treatment model. The clinical team explains both options on arrival so each person can make an informed decision about their detox.
No. Buprenorphine and Suboxone are not legally available to prescribe for addiction treatment in Thailand. If you are currently prescribed Suboxone in your home country, the clinical team manages a taper off buprenorphine as part of your admission. This is covered during the admissions process so there are no surprises on arrival.
Methadone is a long-acting opioid agonist used at Jintara as a short-term taper medication during opioid detox. The attending psychiatrist designs the taper from the opioid used, the dose and how long it has been used. Nursing staff score withdrawal severity with the Clinical Opiate Withdrawal Scale and adjust the medication in response. It is not used for long-term maintenance here.
Yes. A supported cold turkey approach is available, using comfort medications including clonidine. Many people who begin cold turkey choose to switch to methadone within three to four days, once symptoms peak. The switch is available at any point, and the psychiatrist discusses both options at the first assessment.
Most people completing opioid detox at Jintara need a minimum of three weeks before the acute withdrawal phase resolves. For fentanyl the timeline is usually longer, because of potency and tissue accumulation. The three-day rapid detox some facilities advertise is not consistent with how opioid withdrawal actually works. The 30-day program is built to include the full detox phase and the start of the therapeutic work.
No. Methadone here is a taper, not a maintenance prescription. The dose comes down in stages under clinical supervision until it is no longer needed, before or shortly after discharge. The goal is full clearance, not an ongoing prescription.
Yes. Therapy and group sessions start in the first week alongside the detox process. The clinical and nursing teams coordinate daily so the therapeutic program is matched to each person's physical state. Early withdrawal is physically demanding, and the structure of the program is built to accommodate that rather than pause for it.
Jintara is a small adult residential rehab in Chiang Mai with a 3.2:1 staff-to-client ratio. Opioid detox is individualized and medically supervised, with COWS-scored nursing assessments and a psychiatrist-led medication plan throughout, inside a minimum 30-day program.
Jintara Rehab is licensed by the Thai Ministry of Public Health as a rehabilitation centre. The clinical information on this page describes Jintara's general approach to supporting clients during the early recovery period. Medical decisions, including medication protocols, are determined by addiction-specialist psychiatrists through our partner hospital pathway. Individual treatment varies based on clinical assessment. This content is for informational purposes and does not constitute medical advice.